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Platelet-Rich Fibrin (PRF) is a biological preparation derived from the patient’s own blood that concentrates growth factors — proteins that regulate cell migration, proliferation, and differentiation in healing tissue. At Dazzle Dental Clinic, PRF is incorporated into implant surgery, bone grafting, and periodontal procedures to accelerate soft tissue healing, support bone regeneration, and reduce post-operative inflammation.
What PRF Contains and Why It Matters
When blood is drawn and centrifuged without anticoagulants (the L-PRF protocol), it separates into three layers. The buffy coat layer is captured as a fibrin clot containing platelets, leukocytes, and growth factors including PDGF, TGF-β, VEGF, and IGF-1. At Dazzle, L-PRF is prepared using the standard Choukroun protocol. For a full breakdown of PRF types and their different clinical applications, see our PRF applications guide.
Where PRF Is Used at Dazzle
Socket preservation after extraction: PRF plug placed into the extraction socket immediately after tooth removal, combined with bone graft material. Published data: socket closure is significantly faster with PRF versus graft alone; patient reports less post-extraction pain.
Sinus lift augmentation: PRF membrane mixed with xenograft. Published data: sinus lifts with PRF show earlier mineralisation of the graft material — implant placement timelines can be reduced by 4–6 weeks compared to graft alone. See our detailed sinus lift and PRF guide for the full clinical explanation.
Implant placement sites: PRF membrane placed at the implant neck and peri-implant space at placement. Reduces peri-implant soft tissue inflammation during the healing period; supports early soft tissue coverage of the implant shoulder.
Periodontal regenerative surgery: PRF combined with bone graft in infrabony periodontal defects during GTR procedures. Additional growth factor supply to the defect site beyond what the membrane alone provides.
The i-PRF Variant
Injectable PRF (i-PRF) is prepared at lower centrifugation speed, producing a liquid PRF that can be mixed directly with particulate bone graft material to produce a sticky, moldable graft-PRF putty. At Dazzle, i-PRF is used when the surgical site geometry makes membrane application difficult.
FAQs
Q1: Is PRF safe?
Yes. PRF is autologous — prepared from the patient’s own blood, with no donor material, no anticoagulants, and no additives. There is no risk of allergic reaction or disease transmission.
Q2: Does PRF guarantee faster healing?
PRF demonstrably accelerates early healing in published controlled studies — but it does not override the fundamental biology of bone formation or eliminate the need for adequate graft consolidation time. Sinus lifts with PRF are typically ready 4–6 weeks earlier than without PRF. PRF is an adjunct that optimises healing, not a shortcut.
Q3: Is there an additional cost for PRF?
At Dazzle, PRF preparation is included in implant surgery and bone grafting procedures where it is used. It is not an optional upsell charged separately for routine implant cases.
Q4: Can PRF be used if I take blood thinners?
Patients on anticoagulant therapy have altered platelet function or coagulation that affects the quality of the PRF clot formed. The clinical team reviews the patient’s medication list before planning PRF use. This is managed on a case-by-case basis.
